Cracking (Splitting) Blistering is caused by entrapment of gases in or underneath the polymer film due Chipping is related to higher degree of attrition associated with the coating process. Cratering is related to penetration of the coating solution into the surface of the tablet, PittingImportance of Defect Reduction The Role of Automatic Inspection Concurrent benefits Maximizeline speed, quality AND yields WHILE SIMULTANEOUSLY Minimizing manpower, scrap, customer returns. Wide variety of defects in coating and metallizing Voids, streaks, chatter, fibers, gels, spots, dimples, contaminants. Substrate and coated stock. tablet coating defects remedies
Coating Tablet Defects: The Cause and The Remedies 1. The use of lake dyes eliminates dye migration. 2. A reformulation with different plasticizers and additives is the best way to solve film instabilities caused by the ingredients.
Jun 04, 2011 This is a defect where the coating peels away from the tablet surface in a sheet. Peeling indicates that the coating solution did not lock into the tablet surface. This could be due to a defect in the coating solution, overwetting, or high moisture content in the tablet core which prevented the coating to adhering. Chipping Tablet coating defetcs 1. Cause: Over heating during spraying coating solution Remedy: use mild drying condition. Chipping o It is the defect where film become chipped and dented, usually at the edges of tablet. Cause: Excessive attrition during coating process Remedy: Increase hardness of the film. tablet coating defects remedies It is defect of film coating whereby volcaniclike craters appears exposing the tablet surface. The coating solution penetrates the surface of the tablet, often at the crown where the surface is more porous, causing localized disintegration of the core and disruption of the coating. Causes. Inefficient drying. Higher rate of application of coating solution. Remedies. Use efficient and optimum drying
Tablet Coating Problems and their Solutions in Pharmaceuticals Learn how to solve the common problems of coating occurred during the manufacturing of tablets. Ankur Choudhary Print Question Forum 1 comment tablet coating defects remedies How can the answer be improved? Feb 02, 2012 Coating Tablet Defects: The Cause and The Remedies Here is a list of common defects associated with coated tablets and some likely causes and the remedies. This is the result of high pan speed, a friable tablet core, or a coating solution that lacks a good plasticizer Oct 12, 2017# pharmadigest# GPATpreparation# Pharmatorials Problems and Remedies for Tablet Coating in Just 5 Minutes Understand Problems and Remedies for Tablet Coating Blistering, Chipping, CrateringRating: 4.37 / Views: 603